Hydroxyzine Pamoate 25 mg Capsule (Pfizer)

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Hydroxyzine Pamoate doesn't help me stay asleep.

Nov 16, 2011
Review by  
Rated a Very Helpful Review

Pros:generic is cheap/free, not addictive, treats many different things

Cons:doesn't help you to sleep through the night

The Bottom Line: Hydroxyzine Pamoate may be useful for people who stay up late and then can't fall asleep, but it didn't work for me.


I've developed sleeping issues over the past two years.  I don't have a problem falling asleep, but I can't seem to stay asleep.  I usually go to sleep around 8 or 9pm and find myself awake and unable to fall back asleep at 1 or 2am.  I start to get worried about not being able to get any more sleep which makes me axious and prevents the possibility of my falling back asleep.  It is a vicious cycle and one that I really could do without.  I brought the issue up with doctor yet again recently and she prescribed Hydroxyzine Pamoate for me to use.

About This Product

Hydroxyzine Pamoate
is a generic version of the brand name product Vistaril.  It is actually an antihistamine (and mild tranquilizer) that can be used to treat itching, allergies, nausea, vomiting, pain, anxiety, and insomnia.  It comes in 25 milligram capsules and does not have the dependence or addiction issues associated with other anxiety and insomnia medications. 

My Experience

The doctor at my employer's health clinic prescribed Hydroxyzine Pamoate to me after suggesting Benadryl (which, as an asthmatic I'm not supposed to take regularly) and then Ambien (which I refused).  I decided to try it on a Wednesday night because I had the following day off of work so if it totally knocked me out, it wouldn't have a major impact on my day.  The doctor told me to take it right before bed, so I popped a capsule at 8pm when I was already exhausted and headed to bed.  I was asleep within minutes... but then I was wide awake at 1am which disappointed me.  I've never had a problem with falling asleep.  It is the staying asleep that is the problem.

I've taken the Hydroxyzine Pamoate 25 mg Capsules a few more times since then.  What I've learned is that the antihistamine properties do a nice job of helping me to clear out my usually-congested head during the course of the night, but it doesn't help me to stay asleep any more than popping Benadryl or having a couple of drinks ever did. 

If my husband ever went to the doctor for his sleep issues and got a prescription for this stuff, I definitely think it would help him.  He stays up until 11pm or midnight but then can't fall asleep because his mind is racing and he is worrying about work.  I think that Hydroxyzine Pamoate definitely could help him in his situation.  It just doesn't work very well in mine so my next step will probably be trying the more hard-core sleep medications like Ambien or Lunesta.

Overall Opinion

The doctor tried to be conservative in prescribing this medication for me to help me sleep.  Unfortunately, it helped me to fall asleep which is something I've never had a problem with and didn't keep me asleep which is what my main issue has been for the past 2 years.  Hydroxyzine Pamoate is basically like taking Benadryl before bed: it knocks you out for a couple of hours but doesn't actually do anything to keep you sleeping through the night.


Recommend this product? No

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